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ProductsBack/Boc-C1-PEG3-C4-OBn [2381196-81-0]
CgoaEWY7L--EInQjAAAAAOOqESw654.png
CgoaEWY7L--EInQjAAAAAOOqESw654.png
CgoaEWY7L--EInQjAAAAAOOqESw654.png

Boc-C1-PEG3-C4-OBn [2381196-81-0]

Research Use Only
T17646
TargetMol Chemicals
CAS Number2381196-81-0
DownloadMSDS
Product group Chemicals
Molecular Weight410.54
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Boc-C1-PEG3-C4-OBn [2381196-81-0]
  • Delivery Days Customer
    999
  • CAS Number
    2381196-81-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Boc-C1-PEG3-C4-OBn
  • Molecular Formula
    C23H38O6
  • Molecular Weight
    410.54
  • Scientific Description
    Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PEG-based PROTAC linker used in the synthesis of various PROTACs, including PROTAC SGK3 degrader-1. PROTACs consist of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other specifically interacts with the target protein, enabling selective degradation of target proteins via the intracellular ubiquitin-proteasome system[1].
  • Shelf life instruction
    3 years
  • SMILES
    O=C(OC(C)(C)C)COCCOCCOCCCCCCOCC=1C=CC=CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTACDegrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
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