Boc-Val-Pro-Arg-AMC . HCl [65147-04-8]

AdipoGen Life Sciences

Boc-Val-Pro-Arg-AMC . HCl [65147-04-8]

10

65147-04-8

Research Use Only

>98%

C31H45N7O7 . HCl

627.7 . 36.5

Boc-Val-Pro-Arg-AMC is a sensitive fluorogenic peptide substrate for alpha-thrombin (Km = 21 microM, kcat = 109 s-1) and the alpha-thrombin-staphylocoagulase complex (Km = 25 microM, kcat = 89 s-1). It also serves as a substrate vor Kallikrein 5 and 8. Activity is quantified by the release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380nm and emits at 440-460nm when interacting with a target enzyme. This substrate has also been used for the rapid detection of MRSA (methicillin-resistant Staphylococcus aureus). - Chemical. CAS: 70375-24-5 - 65147-04-8 (free base). Formula: C31H45N7O7 . HCl. MW: 627.7 . 36.5. Boc-Val-Pro-Arg-AMC is a sensitive fluorogenic peptide substrate for alpha-thrombin (Km = 21 microM, kcat = 109 s-1) and the alpha-thrombin-staphylocoagulase complex (Km = 25 microM, kcat = 89 s-1). It also serves as a substrate vor Kallikrein 5 and 8. Activity is quantified by the release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380nm and emits at 440-460nm when interacting with a target enzyme. This substrate has also been used for the rapid detection of MRSA (methicillin-resistant Staphylococcus aureus).

O=C1C=C(C)C2=CC=C(NC(C(CCCNC(N)=N)NC(C3N(C(C(NC(OC(C)(C)C)=O)C(C)C)=O)CCC3)=O)=O)C=C2O1.Cl

-20°C,2°C to 8°C

12352200