Boehmenan [57296-22-7]

TargetMol Chemicals

Boehmenan [57296-22-7]

999

Research Use Only

C40H40O12

712.74

(+/-)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.

COc1cc(CCCOC(=O)\C=C\c2ccc(O)c(OC)c2)cc2[C@@H](COC(=O)\C=C\c3ccc(O)c(OC)c3)[C@@H](Oc12)c1ccc(O)c(OC)c1

-20°C

12352200