BORIS antibody

GeneTex

BORIS antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

CTCFL

CCCTC-binding factor like

BORIS; BORIS-like protein; brother of the regulator of imprinted sites; cancer/testis antigen 27; CT27; CTCF-T; dJ579F20.2; HMGB1L1; transcriptional repressor CTCFL

Rabbit

IgG

Transcriptional repressor CTCFL

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

-20°C or -80°C,2°C to 8°C

12352203