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ProductsBack/Boromycin [34524-20-4]
Chemical Structure
Chemical Structure
Chemical Structure

Boromycin [34524-20-4]

Research Use Only
AG-CN2-0166
AdipoGen Life Sciences
CAS Number34524-20-4
DownloadMSDS
Product group Chemicals
Estimated Purity>99%
Molecular Weight879.9
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Boromycin [34524-20-4]
  • Delivery Days Customer
    10
  • CAS Number
    34524-20-4
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Hazard Information
    Warning
  • Molecular Formula
    C45H74BNO15
  • Molecular Weight
    879.9
  • Scientific Description
    Boron-containing macrolide antibiotic [1]. Antibacterial [1]. Antiprotozoal (Plasmodium, Babesia) [2]. Anti-HIV compound [3,6]. Ca2+ homeostasis modulator [4]. Potentiator of bleomycin-induced anti-tumor activity [5]. Used as a chiral selector in capillary electrophoresis [7]. - Chemical. CAS: 34524-20-4. Formula: C45H74BNO15. MW: 879.9. Isolated from Streptomyces sp. Boron-containing macrolide antibiotic. Antibacterial. Antiprotozoal (Plasmodium, Babesia). Anti-HIV compound. Ca2+ homeostasis modulator. Potentiator of bleomycin-induced anti-tumor activity. Used as a chiral selector in capillary electrophoresis.
  • SMILES
    [H][C@@]12O[B-]34O[C@@H](C(=O)O[C@@]([H])(C\C=C/CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@H](C)[C@@]1(O3)O5)[C@@H](C)OC(=O)[C@H]([NH3+])C(C)C)[C@]1(O4)O[C@@]([H])(CC[C@H]1C)C(C)(C)[C@H](O)CCC[C@@H]1C[C@H](OC2=O)[C@@H](C)O1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Structure of boromycin: J.D. Dunitz, et al.; Helv. Chim. Acta 54, 1709 (1971)
  • Antibiotic A 28829: V. Prelog, et al.; US Patent 3,769,418 (1973)
  • Boromycin, an anti-HIV antibiotic: J. Kohno, et al.; Biosci. Biotechnol. Biochem. 60, 1036 (1996)
  • The effect of boromycin on the Ca2+ homeostasis: B. Lakatos, et al.; Mol. Cell Biochem. 231, 15 (2002)
  • Boromycin abrogates bleomycin-induced G2 checkpoint: M. Arai, et al.; J. Antibiot. 57, 662 (2004)
  • Biologically active compounds of semi-metals: T. Rezanka & K. Sigler; Phytochem. 69, 585 (2008) (Review)
  • Study on the use of boromycin as a chiral selector in capillary electrophoresis: V. Maier, et al.; J. Chromatogr. A. 1237, 128 (2012)