Bosentan

MedChem Express

Bosentan [147536-97-8]

10

147536-97-8

Research Use Only

99.98

C27H29N5O6S

551.61

Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively.

O=S(NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC3=CC=CC=C3OC)(C4=CC=C(C(C)(C)C)C=C4)=O

-20°C,2°C to 8°C

12352200