BP Lipid 142

MedChem Express

BP Lipid 142

5

Research Use Only

C45H89NO5

724.19

BP Lipid 142 is derived from patent WO2018170306A1 (Example 102). BP Lipid 142 is an ionizable amine lipid analogous to SM-102. The propanolamine head improves encapsulation of mRNA. The lipid has both esters at C6 and C8 position relative to the amine nitrogen. Ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The primary ester located at C6 is attached with a long (11-carbon) lipid tail. The lipid can be used for mRNA-based therapies.

O=C(CCCCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCO)OCCCCCCCCCCC

12352200