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BP13944

Research Use Only
HY-136797
MedChem Express
Molecular Weight410.47
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BP13944
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C20H44BrNO2
  • Molecular Weight
    410.47
  • Scientific Description
    BP13944 is a potential small molecule inhibitor discovered by high-throughput screening. It can effectively inhibit the expression of dengue virus (DENV) replicons with an EC50 value of 1.03+/-0.09 microM. BP13944 can inhibit the replication or viral RNA synthesis of all four serotypes of DENV, but is ineffective against Japanese encephalitis virus. BP13944 may target the DENV NS3 protease, and the E66G amino acid substitution in the NS3 protease region will cause the virus to become resistant to BP13944. BP13944 has no obvious cytotoxicity. As there is currently no effective dengue vaccine and treatment, BP13944, as an effective small molecule inhibitor, may become a potential agent for the treatment of dengue in the future.
  • SMILES
    CCCCCCCCCCCCCCCC[N+](CO)(CC)CO.[Br-]
  • UNSPSC
    12352200