BPN-15606 (besylate)

MedChem Express

BPN-15606 (besylate)

10

Research Use Only

C29H29FN6O4S

576.64

BPN-15606 besylate is a highly potent, orally active gamma-secretase modulator (GSM), attenuates the production of Abeta42 and Abeta40 by SHSY5Y neuroblastoma cells with IC 50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Abeta42 and Abeta40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance [1] .

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