BPR1K871 [2443767-35-7]
T10592
Overview
- SupplierTargetMol Chemicals
- Product NameBPR1K871 [2443767-35-7]
- Delivery Days Customer14
- CAS Number2443767-35-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameBPR1K871
- Molecular FormulaC25H28ClN7O2S
- Molecular Weight526.05
- Scientific DescriptionBPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of 19 nM and 22 nM, respectively.
- Shelf life instruction3 years
- SMILESCN(C)CCCOc1ccc2c(NCCc3cnc(NC(=O)Nc4cccc(Cl)c4)s3)ncnc2c1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation. Hsu YC et al., 2016 Dec 27, OncotargetRead more
