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Chemical Structure
Chemical Structure
Chemical Structure

BQ-788 . sodium salt [156161-89-6]

Research Use Only
AG-CP3-0012
AdipoGen Life Sciences
CAS Number156161-89-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight640.8 . 23.0
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    BQ-788 . sodium salt [156161-89-6]
  • Delivery Days Customer
    10
  • CAS Number
    156161-89-6
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C34H50N5O7 . Na
  • Molecular Weight
    640.8 . 23.0
  • Scientific Description
    Chemical. CAS: 156161-89-6. Formula: C34H50N5O7 . Na. MW: 640.8 . 23.0. Synthetic. Potent and selective endothelin B receptor (ETBR) antagonist. - Potent and selective endothelin B receptor (ETBR) antagonist.
  • SMILES
    CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C(=O)OC)C2=C1C=CC=C2)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(=O)O[Na]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Clearance of circulating endothelin-1 by ETB receptors in rats: T. Fukuroda, et al.; BBRC 199, 1461 (1994)
  • Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788: K. Ishikawa, et al.; PNAS 91, 4892 (1994)
  • Novel antagonist of endothelin ETB1 and ETB2 receptors, BQ-788: effects on blood vessel and small intestine: H. Karaki, et al.; BBRC 205, 168 (1994)
  • PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat: R.L. Schroeder, et al.; J. Cardiovasc. Pharmacol. 32, 935 (1998)
  • BQ-788, a selective endothelin ETB receptor antagonist: M. Okada & M. Nishikibe; Cardiovasc. Drug Rev. 20, 53 (2002)