Chemical Structure
BQ-788 . sodium salt [156161-89-6]
AG-CP3-0012
CAS Number156161-89-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight640.8 . 23.0
Overview
- SupplierAdipoGen Life Sciences
- Product NameBQ-788 . sodium salt [156161-89-6]
- Delivery Days Customer10
- CAS Number156161-89-6
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC34H50N5O7 . Na
- Molecular Weight640.8 . 23.0
- Scientific DescriptionChemical. CAS: 156161-89-6. Formula: C34H50N5O7 . Na. MW: 640.8 . 23.0. Synthetic. Potent and selective endothelin B receptor (ETBR) antagonist. - Potent and selective endothelin B receptor (ETBR) antagonist.
- SMILESCCCC[C@@H](NC(=O)[C@@H](CC1=CN(C(=O)OC)C2=C1C=CC=C2)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(=O)O[Na]
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Clearance of circulating endothelin-1 by ETB receptors in rats: T. Fukuroda, et al.; BBRC 199, 1461 (1994)
- Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788: K. Ishikawa, et al.; PNAS 91, 4892 (1994)
- Novel antagonist of endothelin ETB1 and ETB2 receptors, BQ-788: effects on blood vessel and small intestine: H. Karaki, et al.; BBRC 205, 168 (1994)
- PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat: R.L. Schroeder, et al.; J. Cardiovasc. Pharmacol. 32, 935 (1998)
- BQ-788, a selective endothelin ETB receptor antagonist: M. Okada & M. Nishikibe; Cardiovasc. Drug Rev. 20, 53 (2002)