BRD-K20733377
HY-169265
Molecular Weight430.48
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameBRD-K20733377
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC23H18N4O3S
- Molecular Weight430.48
- Scientific DescriptionBRD-K20733377 is an inhibitor for Bcl-2, and exhibits selective cytotoxicity against senescent cells, that inhibits the viability of Etoposide (HY-13629)-induced IMR-90 senescent cell with an IC50 of 10.7 microM. BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21 and KI67 in aged mouse model[1].
- SMILESO=C(C1=CC=C(C=C1)C2=CC=CC=C2)NC3=CC=C(C=C3)S(=O)(NC4=NC=CC=N4)=O
- UNSPSC12352200