Brevican Antibody: HRP

Biorbyt

Brevican antibody

16

1 microg/ml of SMC-428 was sufficient for detection of Brevican in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Western Blot, ELISA, ImmunoHistoChemistry

WB (1:1000) ELISA, IHC, WB

Research Use Only

Monoclonal

N294A/6 (Formerly sold as S294A-6)

1 mg/ml

HRP

Bcan

brevican

ALPBRE; BEHAB; brain-enriched hyaluronan-binding protein; brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; brevican core protein-like

Mouse

IgG2b

Brevican core protein

Mouse monoclonal to Brevican (HRP). Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE..

Human, Mouse, Rat

See Manual

12352203