BRI3BP Polyclonal Antibody

Reddot Biotech

BRI3BP Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

BRI3BP

BRI3 binding protein

BNAS1; BRI3-binding protein; cervical cancer 1 proto-oncogene-binding protein KG19; cervical cancer oncogene binding protein; HCCR-1; HCCR-2; HCCRBP-1; HCCRBP-3; I3-binding protein; KG19

Rabbit

IgG

BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

Human, Mouse

-20°C

12352203