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ProductsBack/Brivanib alaninate [649735-63-7]
Chemical Structure
Chemical Structure
Chemical Structure

Brivanib alaninate [649735-63-7]

Research Use Only
SYN-1135
SYNkinase
CAS Number649735-63-7
DownloadDatasheet
Product group Chemicals
Estimated Purity>95%
Molecular Weight441.5
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Overview

  • Supplier
    SYNkinase
  • Product Name
    Brivanib alaninate [649735-63-7]
  • Delivery Days Customer
    10
  • CAS Number
    649735-63-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C22H24FN5O4
  • Molecular Weight
    441.5
  • Scientific Description
    Brivanib inhibits VEGFR-2 with an IC(50) of 25nM and a Ki of 26nM, VEGFR-1 with an IC(50) of 380nM and VEGFR-3 with an IC(50) of 10nM. It also shows selectivity for FGFR-1 with an IC(50) of 148nM, FGFR-2 with an IC(50) of 25nM and FGFR-3 with an IC(50) of 68nM. - Chemical. CAS: 649735-63-7. Formula: C22H24FN5O4. MW: 441.5. Brivanib inhibits VEGFR-2 with an IC(50) of 25nM and a Ki of 26nM, VEGFR-1 with an IC(50) of 380nM and VEGFR-3 with an IC(50) of 10nM. It also shows selectivity for FGFR-1 with an IC(50) of 148nM, FGFR-2 with an IC(50) of 25nM and FGFR-3 with an IC(50) of 68nM.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200