BRPF1B/TRIM24-IN-1 [1242907-48-7]

TargetMol Chemicals

BRPF1B/TRIM24-IN-1 [1242907-48-7]

9

Research Use Only

C24H25N3O7S

499.54

BRPF1B/TRIM24-IN-1 (compound 34) is a potent inhibitor of TRIM24, BRPF1, and BRPF2, with IC50 values of 0.43 microM, 0.34 microM, and 1.75 microM respectively. The dissociation constants (KD) for its binding with the bromodomains of TRIM24, BRPF1, and BRD1 are 222 nM, 137 nM, and 1130 nM respectively.

O=C1N(C2=CC(OC3=CC=C(OC)C=C3)=C(C=C2N1C)NS(=O)(=O)C4=CC=C(OC)C(OC)=C4)C

-20°C

51202000