BTL-MK [2758569-43-4]

TargetMol Chemicals

BTL-MK [2758569-43-4]

16

Research Use Only

C24H24O6

408.44

BTL-MK (Compound 19) is an orally active antiallergic agent that inhibits degranulation of mast cells with an IC50 of 6.7 microM by binding to the inhibitory receptor FcgammaRIIB. BTL-MK improves metabolic stability in human liver microsomes and ameliorates the allergic response in an Ovalbumin-induced food allergy mice model. It exhibits good pharmacokinetic characteristics with metabolic stability [1].

C([C@]1(C(C)=O)C(=C(O)C(=O)O1)C2=CC=C(O)C=C2)C3=CC(CC=C(C)C)=C(O)C=C3

-20°C

12352200