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ProductsBack/BUB1B Recombinant Monoclonal Antibody
Western Blot Positive WB detected in: K562 whole cell lysate, U-251 whole cell lysate All lanes: BubR1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 120, 106, 122 kDa Observed band size: 125 kDa
Western Blot Positive WB detected in: K562 whole cell lysate, U-251 whole cell lysate All lanes: BubR1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 120, 106, 122 kDa Observed band size: 125 kDa
Western Blot Positive WB detected in: K562 whole cell lysate, U-251 whole cell lysate All lanes: BubR1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 120, 106, 122 kDa Observed band size: 125 kDa

BUB1B Recombinant Monoclonal Antibody

Research Use Only
CSB-RA263021A0HU
Cusabio
ApplicationsFlow Cytometry, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetBUB1B
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Overview

  • Supplier
    Cusabio
  • Product Name
    BUB1B Recombinant Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    Flow Cytometry, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    7H4
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID701
  • Target name
    BUB1B
  • Target description
    BUB1 mitotic checkpoint serine/threonine kinase B
  • Target synonyms
    Bub1A; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 homolog beta; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; SSK1
  • Isotype
    IgG
  • Protein IDO60566
  • Protein Name
    Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
  • Scientific Description
    Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203