Bumetanide (sodium) [28434-74-4]
HY-17468A
CAS Number28434-74-4
Product group Chemicals
Molecular Weight386.40
Overview
- SupplierMedChem Express
- Product NameBumetanide (sodium) [28434-74-4]
- Delivery Days Customer10
- CAS Number28434-74-4
- CertificationResearch Use Only
- Molecular FormulaC17H19N2NaO5S
- Molecular Weight386.40
- Scientific DescriptionBumetanide sodium, a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide sodium is a selective NKCC1 inhibitor, and also inhibits NKCC2, with IC50s of 0.68 and 4.0 microM for hNKCC1A and hNKCC2A, respectively[1][2].
- SMILESO=C(O[Na])C1=CC(NCCCC)=C(OC2=CC=CC=C2)C(S(=O)(N)=O)=C1
- UNSPSC12352200