Buparlisib (BKM120)

Selleck Chemicals

Buparlisib (BKM120) [944396-07-0]

9

Research Use Only

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Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110alpha/beta/delta/gamma with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kbeta. Buparlisib induces apoptosis. Phase 2.

-80°C

51202000