BWA-522 intermediate-1

MedChem Express

BWA-522 intermediate-1

14

Research Use Only

99.27

C19H19N3O5

369.37

BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7 [1] .

O=CC1CCN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1

-20°C,2°C to 8°C

12352200