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ProductsBack/c-Fos antibody

c-Fos antibody

GTX129846
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFOS
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Fos antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2353
  • Target name
    FOS
  • Target description
    Fos proto-oncogene, AP-1 transcription factor subunit
  • Target synonyms
    activator protein 1; AP-1; cellular oncogene c-fos; C-FOS; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; Fos proto-oncogene, AP-1 trancription factor subunit; G0/G1 switch regulatory protein 7; p55; proto-oncogene c-Fos
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01100
  • Protein Name
    Proto-oncogene c-Fos
  • Scientific Description
    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • ZEB1 regulates bone metabolism in osteoporotic rats through inducing POLDIP2 transcription.
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  • Region-Dependent Increase of Cerebral Blood Flow During Electrically Induced Contraction of the Hindlimbs in Rats. Chaney R et al., 2022, Front Physiol
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  • Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway. Mutti V et al., 2022 Apr, Mol Neurobiol
    Read more
  • beta-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice. Panayotis N et al., 2021 May 18, Cell Rep Med
    Read more
  • Regulation of stress-provoked aggressive behavior using endocannabinoids. Chang CH et al., 2021 Nov, Neurobiol Stress
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  • Treatment of 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 inhibits TNF-alpha-mediated expression of MMP-9 protein and cell invasion through the suppression of JNK pathway and microRNA 221 in human pancreatic adenocarcinoma cancer cells. Cheng YH et al., 2021, PLoS One
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  • GDF15 promotes glioma stem cell-like phenotype via regulation of ERK1/2-c-Fos-LIF signaling. Zhu S et al., 2021 Jan 11, Cell Death Discov
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  • Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3beta-AP1/Snail and JNK-AP1 pathways. Pan CH et al., 2020 Dec 1, Chem Biol Interact
    Read more
  • Sexual experience with a known male modulates c-Fos expression in response to mating and male pheromone exposure in female mice. Marco-Manclus P et al., 2020 Aug 1, Physiol Behav
    Read more
  • Ozone ultrafine bubble water induces the cellular signaling involved in oxidative stress responses in human periodontal ligament fibroblasts. Leewananthawet A et al., 2019, Sci Technol Adv Mater
    Read more