C15orf23 Polyclonal Antibody

Reddot Biotech

C15orf23 Polyclonal Antibody

5

Western Blot

Research Use Only

Polyclonal

2 mg/ml

Unconjugated

KNSTRN

kinetochore localized astrin (SPAG5) binding protein

C15orf23; HSD11; kinastrin; kinetochore-localized astrin-binding protein; putative TRAF4-associated factor 1; ROCHIS; SKAP; small kinetochore associated protein; small kinetochore-associated protein; small kinetochore-associated protein, kinetochore-localized astrin-binding protein, TRAF4 associated factor 1; TRAF4 associated factor 1; TRAF4AF1

Rabbit

IgG

Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Human

-20°C

12352203