C16orf45 Polyclonal Antibody

Reddot Biotech

C16orf45 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

BMERB1

bMERB domain containing 1

bMERB domain-containing protein 1; C16orf45; migration inhibitory protein; MINP; uncharacterized protein C16orf45

Rabbit

IgG

C16orf45, also known as FLJ32618, is a 204 amino acid protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohns disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Human, Mouse, Rat

-20°C

12352203