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C188 [823828-18-8]
T26936
Overview
- SupplierTargetMol Chemicals
- Product NameC188 [823828-18-8]
- Delivery Days Customer16
- CAS Number823828-18-8
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameC188
- Molecular FormulaC19H15NO7S2
- Molecular Weight433.45
- Scientific DescriptionC188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-gamma-stimulated HepG2 cellular STAT1 phosphorylation.
- Shelf life instruction3 years
- SMILESOC(=O)CSc1cc(NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2c1O
- Storage Instruction-20°C
- UNSPSC12352200