Bio-Connect

C4BPB Polyclonal Antibody

RD252505A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetC4BPB
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    C4BPB Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID725
  • Target name
    C4BPB
  • Target description
    complement component 4 binding protein beta
  • Target synonyms
    C4b-binding protein beta chain; C4BP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203