C8orf4 Polyclonal Antibody

Reddot Biotech

C8orf4 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

TCIM

transcriptional and immune response regulator

C8orf4; human thyroid cancer 1; protein C8orf4; TC1; TC-1; thyroid cancer protein 1; transcriptional and immune response regulator

Rabbit

IgG

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Human, Mouse, Rat

-20°C

12352203