CAD Polyclonal Antibody

Reddot Biotech

CAD Polyclonal Antibody

5

0.7 mg/ml

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

CAD protein; CAD trifunctional protein; CDG1Z; DEE50; EIEE50; GATD4; multifunctional protein CAD

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

-20°C

12352203