Calbindin 1 (CALB1)(CALB1/3333), CF594 conjugate, 0.1mg/mL [26628-22-8]

Biotium

Calbindin 1 (CALB1)(CALB1/3333), CF594 conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

CALB1/3333

0.1 mg/ml

Other Conjugate

CALB1

calbindin 1

CALB; calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; calbindin 27; calbindin D28; D-28K; RTVL-H protein; vitamin D-dependent calcium-binding protein, avian-type

Mouse

IgG2b

Calbindin

Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human

2°C to 8°C

12352203