IHC-P analysis of rat liver tissue using GTX85207 CALHM1 antibody. Working concentration : 5 microg/ml
IHC-P analysis of rat liver tissue using GTX85207 CALHM1 antibody. Working concentration : 5 microg/ml
CALHM1 antibody
GTX85207
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCALHM1
Overview
- SupplierGeneTex
- Product NameCALHM1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID255022
- Target nameCALHM1
- Target descriptioncalcium homeostasis modulator 1
- Target synonymscalcium homeostasis modulator protein 1; FAM26C; family with sequence similarity 26, member C
- HostRabbit
- IsotypeIgG
- Protein IDQ8IU99
- Protein NameCalcium homeostasis modulator protein 1
- Scientific DescriptionAlzheimers disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-b (Ab) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Ab levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203