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CALP1 TFA

T75791
TargetMol Chemicals
Molecular Weight956.1
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CALP1 TFA
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CALP1 TFA
  • Molecular Formula
    C42H76F3N9O12
  • Molecular Weight
    956.1
  • Scientific Description
    CALP1 TFA, a calmodulin (CaM) agonist with a dissociation constant (Kd) of 88 microM, selectively binds to the CaM EF-hand/Ca2+-binding site, inhibiting calcium channel opening. This action blocks calcium influx and apoptosis with an IC50 of 44.78 microM, modulates glutamate receptor channel activity, and impedes a store-operated nonselective cation channel. Additionally, CALP1 TFA enhances CaM-dependent phosphodiesterase activity, denoting its multifaceted role in modulating cellular calcium dynamics [1] [2] [3] [4].
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200