Calpain S1 antibody [AT1D11]

GeneTex

Calpain S1 antibody [AT1D11]

9

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

AT1D11

1 mg/ml

Unconjugated

CAPNS1

calpain small subunit 1

calcium-activated neutral proteinase small subunit; calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4, small subunit (30K); calpain regulatory subunit; calpain small subunit 1; calpain, small polypeptide; CALPAIN4; CANP; CANP small subunit; CANPS; CAPN4; CDPS; CSS1; epididymis secretory sperm binding protein

Mouse

IgG1

Calpain small subunit 1

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203