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Calphostin C

BS-75207C
Bioss Antibodies
Estimated Purity>95%
Product group Chemicals
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Overview

  • Supplier
    Bioss Antibodies
  • Product Name
    Calphostin C [121263-19-2]
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Potent and highly specific cell permeable protein kinase C (PKC) inhibitor [1]. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000