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Calretinin / Calbindin 2 (Mesothelioma Marker)(CALB2/2786), CF647 conjugate, 0.1mg/mL [26628-22-8]

Calretinin / Calbindin 2 (Mesothelioma Marker)(CALB2/2786), CF647 conjugate, 0.1mg/mL [26628-22-8]

BNC472786
Biotium
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCALB2
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Overview

  • Supplier
    Biotium
  • Product Name
    Calretinin / Calbindin 2 (Mesothelioma Marker)(CALB2/2786), CF647 conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CALB2/2786
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID794
  • Target name
    CALB2
  • Target description
    calbindin 2
  • Target synonyms
    29 kDa calbindin; CAB29; CAL2; calbindin 2, (29kD, calretinin); calbindin D29K; calretinin; CR; testicular secretory protein Li 8
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP22676
  • Protein Name
    Calretinin
  • Scientific Description
    Calretinin (also known as Calbindin 2) is a member of the troponin C superfamily. Proteins in this family have 6 EF-hand domains which bind to calcium. Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibodies to calretinin are useful in differentiating mesothelioma from adenocarcinomas of the lung. They can also aid in differentiating adrenal cortical neoplasms from pheochromocytomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

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Figure 1. IHC analysis of Calretinin/CALB2 using anti-Calretinin/CALB2 antibody (A04255). Calretinin/CALB2 was detected in paraffin-embedded section of human rectal cancer tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1microg/ml rabbit anti-Calretinin/CALB2 Antibody (A04255) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB as the chromogen.
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