IHC image of CSB-PA822299LA01HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
CAMKK2 Antibody
CSB-PA822299LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCAMKK2
Overview
- SupplierCusabio
- Product NameCAMKK2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10645
- Target nameCAMKK2
- Target descriptioncalcium/calmodulin dependent protein kinase kinase 2
- Target synonymscalcium/calmodulin-dependent protein kinase beta; calcium/calmodulin-dependent protein kinase kinase 2; calcium/calmodulin-dependent protein kinase kinase 2, beta; caM-kinase kinase 2; caM-kinase kinase beta; CAMKK; caM-KK 2; caM-KK beta; CAMKK beta protein; CAMKKB
- HostRabbit
- IsotypeIgG
- Protein IDQ96RR4
- Protein NameCalcium/calmodulin-dependent protein kinase kinase 2
- Scientific DescriptionCalcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203