CAMLG Polyclonal Antibody
RD81583A
TargetCAMLG
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameCAMLG Polyclonal Antibody
- Delivery Days Customer5
- Concentration1 mg/ml
- Gene ID819
- Target nameCAMLG
- Target descriptioncalcium modulating ligand
- Target synonymscalcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; CAML; cyclophilin B-binding protein; GET2; guided entry of tail-anchored proteins factor CAMLG
- Scientific DescriptionThe immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
- Storage Instruction-20°C
- UNSPSC12352203