Bio-Connect

CAMLG Polyclonal Antibody

RD81583A
Reddot Biotech
TargetCAMLG
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CAMLG Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID819
  • Target name
    CAMLG
  • Target description
    calcium modulating ligand
  • Target synonyms
    calcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; CAML; cyclophilin B-binding protein; GET2; guided entry of tail-anchored proteins factor CAMLG
  • Scientific Description
    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203