CAND1 Polyclonal Antibody

Reddot Biotech

CAND1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

CAND1

cullin associated and neddylation dissociated 1

cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP-interacting protein of 120 kDa A; TIP120; TIP120A

Rabbit

IgG

This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.

Human, Mouse, Rat

-20°C

12352203