CAPS1 antibody

GeneTex

CAPS1 antibody

9

Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

WB: 0.5 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

1 mg/ml

Liquid

CADPS

calcium dependent secretion activator

Ca++-dependent secretion activator; Ca2+ dependent secretion activator; Ca2+-dependent activator protein for secretion; Ca2+-regulated cytoskeletal protein; CADPS1; calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1; CAPS; CAPS1; CAPS-1; UNC-31

Calcium-dependent secretion activator 1

CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

-20°C or -80°C,2°C to 8°C

12352203