Chemical Structure
Carbamoylcholine chloride [51-83-2]
AG-CR1-3649
CAS Number51-83-2
Product group Chemicals
Estimated Purity>98%
Molecular Weight147.3 . 35.4
Overview
- SupplierAdipoGen Life Sciences
- Product NameCarbamoylcholine chloride [51-83-2]
- Delivery Days Customer10
- ADR Class6.1
- CAS Number51-83-2
- CertificationResearch Use Only
- Estimated Purity>98%
- Hazard InformationDanger,Excepted quantity
- Molecular FormulaC6H15N2O2 . Cl
- Molecular Weight147.3 . 35.4
- Scientific DescriptionAcetylcholine analog that activates acetylcholine receptors (AChR). Non-selective agonist of nicotinic (nAChR) and muscarinic (mAChR) receptors that is resistant to the action of cholinesterases. Used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility and neuronal signaling. Shown to inhibit apoptotic death of cultured neurons. - Chemical. CAS: 51-83-2. Formula: C6H15N2O2 . Cl. MW: 182.7. Acetylcholine analog that activates acetylcholine receptors (AChR). Non-selective agonist of nicotinic (nAChR) and muscarinic (mAChR) receptors that is resistant to the action of cholinesterases. Used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility and neuronal signaling. Shown to inhibit apoptotic death of cultured neurons.
- SMILESNC(OCC[N+](C)(C)C)=O.[Cl-]
- Storage Instruction-20°C,2°C to 8°C
- UN NumberUN 2811
- UNSPSC12352200
References
- Activation of muscarinic cholinergic receptors blocks apoptosis of cultured cerebellar granule neurons: G.M. Yan, et al.; Mol. Pharmacol. 47, 248 (1995)
- Carbamoylcholine homologs: Novel and potent agonists at neuronal nicotinic acetylcholine receptors: A.A. Jensen, et al.; Mol. Pharmacol. 64, 865 (2003)
- The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells: Y. Xiao & K.J. Kellar; J. Pharmacol. Exp. Ther. 310, 98 (2004)
- Distinct pathways of ERK activation by the muscarinic agonists pilocarpine and carbachol in a human salivary cell line: A.L. Lin, et al.; Am. J. Physiol. Cell Physiol. 294, C1454 (2008)
- K+ACh channel activation with carbachol increases atrial ANP release: D.Y. Xu, et al.; Life Sci. 82, 1083 (2008)
- IL-17A induces hypo-contraction of intestinal smooth muscle via induction of iNOS in muscularis macrophages: D. Mori, et al.; J. Pharmacol. Sci. 125, 394 (2014)