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Chemical Structure
Chemical Structure
Chemical Structure

Carbamoylcholine chloride [51-83-2]

Research Use Only
AG-CR1-3649
AdipoGen Life Sciences
CAS Number51-83-2
Product group Chemicals
Estimated Purity>98%
Molecular Weight147.3 . 35.4
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Carbamoylcholine chloride [51-83-2]
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • CAS Number
    51-83-2
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C6H15N2O2 . Cl
  • Molecular Weight
    147.3 . 35.4
  • Scientific Description
    Acetylcholine analog that activates acetylcholine receptors (AChR). Non-selective agonist of nicotinic (nAChR) and muscarinic (mAChR) receptors that is resistant to the action of cholinesterases. Used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility and neuronal signaling. Shown to inhibit apoptotic death of cultured neurons. - Chemical. CAS: 51-83-2. Formula: C6H15N2O2 . Cl. MW: 182.7. Acetylcholine analog that activates acetylcholine receptors (AChR). Non-selective agonist of nicotinic (nAChR) and muscarinic (mAChR) receptors that is resistant to the action of cholinesterases. Used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility and neuronal signaling. Shown to inhibit apoptotic death of cultured neurons.
  • SMILES
    NC(OCC[N+](C)(C)C)=O.[Cl-]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    UN 2811
  • UNSPSC
    12352200

References

  • Activation of muscarinic cholinergic receptors blocks apoptosis of cultured cerebellar granule neurons: G.M. Yan, et al.; Mol. Pharmacol. 47, 248 (1995)
  • Carbamoylcholine homologs: Novel and potent agonists at neuronal nicotinic acetylcholine receptors: A.A. Jensen, et al.; Mol. Pharmacol. 64, 865 (2003)
  • The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells: Y. Xiao & K.J. Kellar; J. Pharmacol. Exp. Ther. 310, 98 (2004)
  • Distinct pathways of ERK activation by the muscarinic agonists pilocarpine and carbachol in a human salivary cell line: A.L. Lin, et al.; Am. J. Physiol. Cell Physiol. 294, C1454 (2008)
  • K+ACh channel activation with carbachol increases atrial ANP release: D.Y. Xu, et al.; Life Sci. 82, 1083 (2008)
  • IL-17A induces hypo-contraction of intestinal smooth muscle via induction of iNOS in muscularis macrophages: D. Mori, et al.; J. Pharmacol. Sci. 125, 394 (2014)