Carboxypeptidase E antibody

GeneTex

Carboxypeptidase E antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

CPE

carboxypeptidase E

carbocypeptidase E; carboxypeptidase E; carboxypeptidase H; cobalt-stimulated chromaffin granule carboxypeptidase; CPH; enkephalin convertase; epididymis secretory sperm binding protein; IDDHH; insulin granule-associated carboxypeptidase; prohormone-processing carboxypeptidase

Rabbit

IgG

Carboxypeptidase E

This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015]

-20°C or -80°C,2°C to 8°C

12352203