CARD16 Polyclonal Antibody

Reddot Biotech

CARD16 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.1 mg/ml

Unconjugated

CARD16

caspase recruitment domain family member 16

CARD only domain-containing protein 1; CARD only protein; CARD-only protein 1; caspase recruitment domain-containing protein 16; caspase recruitment domain-only protein 1; caspase-1 dominant-negative inhibitor pseudo-ICE; caspase-1 inhibitor COP; COP; COP1; LLID-114769; pseudo interleukin-1 beta converting enzyme; pseudo interleukin-1beta converting enzyme; PSEUDO-ICE; pseudo-IL1B-converting enzyme

Rabbit

IgG

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Human

-20°C

12352203