ProductsBack/Cardiac Troponin I antibody [19C7] (Biotin)

Cardiac Troponin I antibody [19C7] (Biotin)

Name: Cardiac Troponin I antibody [19C7] (Biotin)
SKU: GTX38806_G10
Availability: BackOrder

GTX38806

ApplicationsWestern Blot, ELISA, Other Application

Product group Antibodies

ReactivityHuman

TargetTNNI3

Overview

Supplier
GeneTex
Product Name
Cardiac Troponin I antibody [19C7] (Biotin)
Delivery Days Customer
9
Applications
Western Blot, ELISA, Other Application
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
19C7
Concentration
1.40 mg/ml
Conjugate
Biotin
Gene ID7137
Target name
TNNI3
Target description
troponin I3, cardiac type
Target synonyms
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI, troponin I, cardiac muscle, cardiomyopathy, dilated 2A (autosomal recessive), troponin I type 3 (cardiac)
Host
Mouse
Isotype
IgG2b
Protein IDP19429
Protein Name
Troponin I, cardiac muscle
Scientific Description
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
Reactivity
Human
Storage Instruction
2°C to 8°C
UNSPSC
12352203

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Garza JT, Cote GL. Collection Method of SERS Active Nanoparticles for Sensitive and Precise Measurements. Anal Chem. 2017,89(24):13120-13127. doi: 10.1021/acs.analchem.7b02318
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Miyazaki Y, Ikeda Y, Shiraishi K, et al. Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling. PLoS One. 2012,7(4):e35875. doi: 10.1371/journal.pone.0035875
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Aoyama H, Ikeda Y, Miyazaki Y, et al. Isoform-specific roles of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated Ca(2+) cycling. Cardiovasc Res. 2011,89(1):79-88. doi: 10.1093/cvr/cvq252
Read this paper