Cardiac Troponin I antibody [4C2]

GeneTex

Cardiac Troponin I antibody [4C2]

9

No cross-reactivity with skeletal muscle TnI.

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation

Research Use Only

Monoclonal

4C2

Unconjugated

TNNI3

troponin I3, cardiac type

cardiomyopathy, dilated 2A (autosomal recessive); CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1; troponin I type 3 (cardiac); troponin I, cardiac muscle

Mouse

IgG2a

Troponin I, cardiac muscle

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Bovine, Canine, Feline, Goat, Human, Mouse, Porcine, Rabbit, Rat

2°C to 8°C

12352203