Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 10 antibody.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 10 antibody.
CASP10 Antibody
CSB-PA072389
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCASP10
Overview
- SupplierCusabio
- Product NameCASP10 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID843
- Target nameCASP10
- Target descriptioncaspase 10
- Target synonymsALPS2; apoptotic protease MCH-4; CASP-10; caspase 10 apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine protease; caspase-10; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; FLICE-2; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; MCH4
- HostRabbit
- IsotypeIgG
- Protein IDQ92851
- Protein NameCaspase-10
- Scientific DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp- - -AMC and Asp-Glu-Val-Asp- - -AMC. Isoform C is proteolytically inactive. Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646. Ingo H. Engels, Mol. Cell. Biol., Apr 2005; 25: 2808 - 2818. Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806. Jin Wang, PNAS, Nov 2001; 98: 13884.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203