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CASP10 antibody

Research Use Only
ORB66964
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCASP10
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Overview

  • Supplier
    Biorbyt
  • Product Name
    CASP10 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID843
  • Target name
    CASP10
  • Target description
    caspase 10
  • Target synonyms
    ALPS2; apoptotic protease MCH-4; CASP-10; caspase 10 apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine protease; caspase-10; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; FLICE-2; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; MCH4
  • Host
    Rabbit
  • Protein IDQ92851
  • Protein Name
    Caspase-10
  • Scientific Description
    Rabbit polyclonal to CASP10.Caspase 10 (CASP10) belongs to the peptidase C14A family, which is involved in the activationcascade of caspases responsible for apoptosis execution. CASP10 is recruited to both Fas-andTNFR-1 receptors in a FADD dependent manner, and may participate in the granzyme B apoptoticpathways. CASP10 cleaves and activates caspase-3, -4, -6, -7, -8, and -9, and hydrolyzes the smallmoleculesubstrates, Tyr-Val-Ala-Asp- - -AMC and Asp-Glu-Val-Asp- - -AMC. Defects in CASP10 havebeen implicated in autoimmune lymphoproliferative syndrome type 2A (ALPS2A), familial non-Hodgkin lymphoma (NHL) and gastric cancer (GASC).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203