CASP3 Antibody
CSB-PA240326
Overview
- SupplierCusabio
- Product NameCASP3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp- - -Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Gervais, F. G et al.Cell 97: 395-406, 1999. Nicholson, D. W. et al. (1995) Nature 376, 37-43.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203