IHC-P analysis of human lung carcinoma tissue using GTX86952 Caspase 3 (cleaved Asp175) antibody.
IHC-P analysis of human lung carcinoma tissue using GTX86952 Caspase 3 (cleaved Asp175) antibody.
Caspase 3 (cleaved Asp175) antibody
GTX86952
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCASP3
Overview
- SupplierGeneTex
- Product NameCaspase 3 (cleaved Asp175) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID836
- Target nameCASP3
- Target descriptioncaspase 3
- Target synonymsapopain; CASP-3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; CPP32; CPP-32; CPP32B; cysteine protease CPP32; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1
- HostRabbit
- IsotypeIgG
- Protein IDP42574
- Protein NameCaspase-3
- Scientific DescriptionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimers disease. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Anti-Interleukin-16-Neutralizing Antibody Attenuates Cardiac Inflammation and Protects against Cardiac Injury in Doxorubicin-Treated Mice. Zhang J et al., 2021, Mediators InflammRead more
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- Cinnamaldehyde and Hyperthermia Co-Treatment Synergistically Induces ROS-Mediated Apoptosis in ACHN Renal Cell Carcinoma Cells. Ahn CR et al., 2020 Sep 17, BiomedicinesRead more
- Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice. Xu Y et al., 2020 Jul 23, Aging (Albany NY)Read more
- Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo. Wang YY et al., 2020 Mar 31, ACS OmegaRead more