CASPR antibody

GeneTex

CASPR antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.53 mg/ml

Unconjugated

Cntnap1

contactin associated protein-like 1

AI841080; C; Caspr; caspr1; contactin-associated protein 1; MHDNIV; NC; NCP1; neurexin 4 (contactin associated protein); neurexin IV; neurexin-4; Nr; Nrxn4; p; p19; p190; paranodin; sh; shm

Rabbit

IgG

Contactin-associated protein 1

Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells. Mice that lack CNTAP1 exhibit tremor, ataxia, and significant motor paresis. Normal paranodal junctions fail to form, and the organization of the paranodal loops is disrupted. Contactin is undetectable in the paranodes, and potassium channels are displaced from the juxtaparanodal into the paranodal domains. Also results in a severe decrease in peripheral nerve conduction velocity.

Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203