Bio-Connect

Caspr2 antibody [N2N3]

GTX109389
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCNTNAP2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Caspr2 antibody [N2N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID26047
  • Target name
    CNTNAP2
  • Target description
    contactin associated protein 2
  • Target synonyms
    AUTS15; CASPR2; CDFE; cell recognition molecule Caspr2; contactin associated protein like 2; contactin-associated protein-like 2; homolog of Drosophila neurexin IV; NRXN4; PTHSL1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UHC6
  • Protein Name
    Contactin-associated protein-like 2
  • Scientific Description
    This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sortilin acts as an endocytic receptor for alpha-synuclein fibril.
    Read more