CAST Polyclonal Antibody
RD79946A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAST
Overview
- SupplierReddot Biotech
- Product NameCAST Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID831
- Target nameCAST
- Target descriptioncalpastatin
- Target synonymsBS-17; calpain inhibitor; calpastatin; PLACK; sperm BS-17 component
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203